Successful Occlusion of the Splenic Artery Using the Endoluminal Occlusion System

Occlusion of blood vessels with the use of endovascular techniques is a fundamental concept for interventional management of urgent and emergent vascular conditions (1,2). However, complete and durable vessel occlusion is difficult to achieve with the currently available mechanical devices, most common among which are coils or plugs. The endoluminal occlusion system (EOS; ArtVentive, Carlsbad, California) is a family of catheter-based, expandable endoluminal mechanical occlusion devices. The possible clinical indications of the EOS device include management of venous (eg, varicocele, ovarian varices, varicose veins) and arterial (eg, emergency arterial embolization in trauma patients) conditions. As no late imaging was obtained in the present case, durable occlusion with the EOS device could be assessed in future studies.
To conclude, the EOS may provide a safe and reliable method of immediate vessel occlusion in the peripheral arterial circulation.

A New Occlusion Device: Application of the ArtVentive Endoluminal Occlusion System (EOS)—First in Human Clinical Trial

Purpose: The purpose of this study was to determine the safety and efficacy of a new endoluminal occlusion device, ArtVentive endoluminal occlusion system (EOS™), to occlude the spermatic vein in symptomatic males with varicoceles.
Methods: The ArtVentive EOS™device has been developed for percutaneous occlusion of the peripheral arterial and venous vasculature.
Results: The acute occlusion rate at the end of the procedure was 100 % occurring in nine of nine vessels. The spermatic veins of all patients remained occluded on venography at 30 days follow-up. Pain scores related to varicoceles decreased in five of six patients.
Conclusions: Although we recognize this study is limited, initial experience indicates that the ArtVentive EOS™ is a safe and effective new device for occlusion of vessels (varicoceles). The device has potential applications in other clinical conditions requiring occlusion of veins or arteries.